Dr Nancy Malek

BVSc (Hons) MBBS DipClin (Hyp) FANZCA

Strength of Association

Three-year outcomes of post-acute sequelae of COVID-19

Cai, M., Xie, Y., Topol, E. J. et al.

Nature Medicine (2024)

DOI: 10.1038/s41591-024-02987-8

Consistency

Long COVID in Young Children, School-Aged Children, and Teens

Gross, R. S., Carmilani, M., Stockwell, M. S. et al.

JAMA Pediatrics (2025)

DOI: 10.1001/jamapediatrics.2025.1415

Characterizing Long COVID in Children and Adolescents

Gross, R. S., Thaweethai, T., Kleinman, L. C. et al.

JAMA (2024)

DOI: 10.1001/jama.2024.12747

Characterizing Long COVID Symptoms During Early Childhood

Gross, R. S., Thaweethai, T., Salisbury, A. L. et al.

JAMA Pediatrics (2025)

DOI: 10.1001/jamapediatrics.2025.1066

Specificity

Association Between COVID-19 Infection and Thyroid Cancer Development: A Retrospective Cohort Study Using the TriNetX Database

Wang, H.-Y., Lin, Y.-C., Hou, J.-U. et al.

Biomedicines (2025)

DOI: 10.3390/biomedicines13081933

Respiratory viral infections awaken metastatic breast cancer cells in lungs

Chia, S. B., Johnson, B. J., Hu, J. et al.

Nature (2025)

DOI: 10.1038/s41586-025-09332-0

SARS-CoV-2 infection heightens the risk of developing HPV-related carcinoma in situ and cancer

Shih, Y.-H., Yang, C.-Y., Lung, C.-C. et al.

Discover Oncology (2025)

DOI: 10.1007/s12672-025-03403-4

COVID-19 infection was associated with poor sperm quality: a cross-sectional and longitudinal clinical observation study

Yuan, L., Sun, W., Dong, Z. et al.

Scientific Reports (2025)

DOI: 10.1038/s41598-025-94570-5

COVID-19 infection may reduce serum testosterone levels and increase the risk of erectile dysfunction: A two-sample Mendelian randomization study

Wang, T., Li, C., Song, J. et al.

Investigative and Clinical Urology (2025)

DOI: 10.4111/icu.20240384

Comparing risk of post infection erectile dysfunction following SARS Coronavirus 2 stratified by acute and long COVID, hospitalization status, and vasopressor administration: a U.S. large claims database analysis

Grutman, A. J., Gilliam, K., Maremanda, A. P. et al.

International Journal of Impotence Research (2024)

DOI: 10.1038/s41443-024-00913-7

Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing

Manganotti, P., Iscra, K., Furlanis, G. et al.

Scientific Reports (2025)

DOI: 10.1038/s41598-025-04815-6

Persistent neurocognitive deficits in long COVID: Evidence of structural changes and network abnormalities following mild infection

Samanci, B., Ay, U., Gezegen, H. et al.

Cortex (2025)

DOI: 10.1016/j.cortex.2025.04.004

Temporality

SARS-CoV-2 is associated with changes in brain structure in UK Biobank

Douaud, G., Lee, S., Alfaro-Almagro, F. et al.

Nature (2022)

DOI: 10.1038/s41586-022-04569-5

Dose-Response

SARS-COV-2 re-infection and incidence of post-acute sequelae of COVID-19 (PASC) among essential workers in New York: a retrospective cohort study

Babalola, T. K., Clouston, S. A., Sekendiz, Z. et al.

The Lancet Regional Health - Americas (2025)

DOI: 10.1016/j.lana.2024.100984

Acute and postacute sequelae associated with SARS-CoV-2 reinfection

Bowe, B., Xie, Y., Al-Aly, Z. et al.

Nature Medicine (2022)

DOI: 10.1038/s41591-022-02051-3

Biological Plausibility

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

Lan, J., Ge, J., Yu, J. et al.

Nature (2020)

DOI: 10.1038/s41586-020-2180-5

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

Proal, A. D., VanElzakker, M. B., Aleman, S. et al.

Nature Immunology (2023)

DOI: 10.1038/s41590-023-01601-2

Tissue-based T cell activation and viral RNA persist for up to 2 years after SARS-CoV-2 infection

Peluso, M. J., Ryder, D., Flavell, R. R. et al.

Science Translational Medicine (2024)

DOI: 10.1126/scitranslmed.adk3295

Coherence

SARS-CoV-2 damages cardiomyocyte mitochondria and implicates long COVID-associated cardiovascular manifestations

Che, W., Guo, S., Wang, Y. et al.

Journal of Advanced Research (2025)

DOI: 10.1016/j.jare.2025.05.013

COVID-19 accelerates vascular aging

Walters & Hannah

Nature Aging (2025)

DOI: 10.1038/s43587-025-00972-5

Incidence of Deep Vein Thrombosis in Patients With COVID-19: A Systematic Review

Secades, D., Dufner Krieger, S., Hidalgo Ramos, R. A. et al.

Cureus (2025)

DOI: 10.7759/cureus.88697

Experiment

Masks and respirators for prevention of respiratory infections: a state of the science review

Greenhalgh, T., MacIntyre, C. R., Baker, M. G. et al.

Clinical Microbiology Reviews (2024)

DOI: 10.1128/cmr.00124-23

COVID-19: Performance study of microplastic inhalation risk posed by wearing masks

Li, L., Zhao, X., Li, Z. et al.

Journal of Hazardous Materials (2021)

DOI: 10.1016/j.jhazmat.2020.124955

“SARS-CoV-2 airborne detection within different departments of a COVID-19 hospital building and evaluation of air cleaners in air viral load reduction”

Frydas, I. S., Kermenidou, M., Karypidou, M. et al.

Journal of Aerosol Science (2025)

DOI: 10.1016/j.jaerosci.2025.106587

Impact of vaccination on the association of COVID-19 with cardiovascular diseases: An OpenSAFELY cohort study

Cezard, G. I., Denholm, R. E., Knight, R. et al.

Nature Communications (2024)

DOI: 10.1038/s41467-024-46497-0

Effectiveness of COVID-19 vaccines against post-COVID-19 condition/long COVID: systematic review and meta-analysis

Peine, C., Stoliaroff-Pepin, A., Reinacher, U. et al.

Clinical Microbiology and Infection (2025)

DOI: 10.1016/j.cmi.2025.07.026

Myocarditis following COVID‐19 vaccine: incidence, presentation, diagnosis, pathophysiology, therapy, and outcomes put into perspective. A clinical consensus document supported by the Heart Failure Association of the European Society of Cardiology (ESC) and the ESC Working Group on Myocardial and Pericardial Diseases

Heidecker, B., Dagan, N., Balicer, R. et al.

European Journal of Heart Failure (2022)

DOI: 10.1002/ejhf.2669